Author
Johns Hopkins UniversityORCID 0000-0003-1458-0897Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Vincent M. Lowe, Ally K. Smith, Rinky D. Parakra…·Daniel Joseph Deredge
MInt-HDX improves protein-ligand docking by integrating HDX-MS data with machine learning and physics-based methods to enhance docking accuracy and ligand pose ranking.
Lydia J. Kramer, Steven L. Austin, Ananya K. Majumdar…·Caren L. Freel Meyers
This study investigates how aromatic residues in E. coli DXPS stabilize the closed conformation of the enzyme during catalysis by analyzing mutagenesis effects on conformational dynamics.
Charles R. Nosal, Ananya K. Majumdar, Netzahualcóyotl Arroyo‐Currás, Caren L. Freel Meyers
This study investigates how trihydroxybenzaldoximes inhibit ThDP-dependent DXP synthase by acting as redox cycling agents, showing their oxidation under aerobic conditions enhances inhibitory activity.