Rebecca L. Harper

The paper defines the role of smooth muscle cells in ECM remodeling during human wound healing and identifies TIMP1 as a key factor in effective repair.

The paper introduces APAS, a method to generate environmentally relevant micro- and nanoplastics by simulating natural aging processes, and shows its ability to produce complex particles with physicochemical properties similar to real-world MNPs.

This study identifies a novel fibroblast subcluster, Fibro-Cthrc1, as a driver of aortic fibrosis in hypertension using scRNA-seq and validates its association with blood pressure in humans.

This study uses single-cell multiomic analysis to identify transcriptional circuits driving non-ischemic cardiac fibrosis in mouse and human hearts, showing reversibility of fibrosis-related changes.

This study identifies de novo LYN variants causing constitutive Lyn kinase activation, leading to neutrophilic vasculitis and liver fibrosis, and shows therapeutic response to Src kinase inhibitors.