Author
University of OxfordORCID 0000-0003-1465-8543Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matthew G Williamson, Rachel Heon‐Roberts, Sarah N. J. Franks…·Brent James Ryan
This study shows USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms, enhancing mitophagy and mitochondrial efficiency in neurons.
Helle Bogetofte, Brent James Ryan, Pia Jensen…·Richard Wade‐Martins
This study uses a novel proteomics platform to identify PTM dysregulation in GBA-N370S PD neurons, revealing impaired neuritogenesis and a role for tau.
Jack P. Connor, Steven D. Quinn, Charley Schaefer
This study develops a molecular model to investigate how hydrophobicity drives amyloid beta aggregation, showing that A{beta}1-42 enrichment in plaques is due to hydrophobic interactions promoting phase separation.