Sam Peters

This study shows that cellular senescence disrupts liver zonation and hepatocyte function with age by altering gene expression and cell signaling.

The paper introduces the SenNet Portal, a resource for senescent cell data and tools, and discusses its usage and future developments.

CoPro identifies spatially coordinated gene expression programs across tissues, revealing distinct cellular states and their interactions in colon, brain, liver, and kidney.

The paper develops a method for efficient multi-kilobase knock-ins in mice and cell lines using CRISPR/Cas9 and rAAV donors, and introduces LOCK-seq for comprehensive characterization of the edited genome.

This study identifies MAGE antigens as markers of tumor heterogeneity and species-specificity in group 3 medulloblastoma, showing their role in cell survival and potential as therapeutic targets.

This paper demonstrates that thalamocortical assembloids formed from human organoids exhibit functional glutamatergic synapses with short-term plasticity and distinct long-term potentiation and depression mechanisms compared to rodents.