Mary H. Patton

This study shows chronic alcohol exposure reduces GABAergic synapses and perineuronal nets on striatal fast-spiking interneurons, promoting increased ethanol consumption.

This study identifies striatal hypercholinergic state and thalamostriatal disruption as causes of amotivation in a 22q11DS mouse model.

This paper demonstrates that thalamocortical assembloids formed from human organoids exhibit functional glutamatergic synapses with short-term plasticity and distinct long-term potentiation and depression mechanisms compared to rodents.