Mukesh Bansal

This study shows that moderate global lowering of mutant Huntingtin in a HD mouse model delays some deficits but benefits diminish over time, suggesting long-term mHtt lowering may be needed for sustained benefit.

The paper identifies widespread transcription initiation at microsatellites across species and develops deep learning models to predict STR-associated transcription and its impact on disease variants.

The paper infers protein kinase pathways in lung adenocarcinoma using phosphotyrosine data and validates them with SILAC assays, revealing novel substrates and synergistic drug responses.

The paper develops an algorithm to deconvolve bulk tumor gene expression data and identifies consistent functional subtypes in pancreatic cancer epithelium and stroma.