Molecular BiologyiSciencePeer-reviewed
Targeting androgen regulation of TMPRSS2 and ACE2 as a therapeutic strategy to combat COVID-19
Qu Deng, Reyaz ur Rasool, Ronnie M. Russell…·Irfan Ahmed Asangani
This study shows androgen regulates ACE2 and TMPRSS2, both critical for SARS-CoV-2 entry, and demonstrates that inhibiting TMPRSS2 or androgen signaling reduces viral entry.