Author

Qu Deng

University of PennsylvaniaORCID 0000-0003-0030-2511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Irfan Ahmed AsanganiiD· 2 shared Ramakrishnan NatesaniD· 2 shared Aqsa Yashfeen· 1 shared Arul M. ChinnaiyaniD· 1 shared Benjamin Garcia· 1 shared David M. FeldseriD· 1 shared Erick Mitchell-VelasqueziD· 1 shared Hyein Cho· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Irfan Ahmed AsanganiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 1, 2026

NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation

Qu Deng, Erick Mitchell-Velasquez, Sharan Venkatesh…·Irfan Ahmed Asangani

This study identifies NNMT as a tumor suppressor in prostate cancer that regulates SAM availability, mTORC1 signaling, and chromatin methylation, revealing a therapeutic strategy using dietary methionine restriction and mTORC1 inhibition.

DOI 10.64898/2026.06.30.734970

mousehuman

𝕏 PostBluesky

Molecular BiologyiSciencePeer-reviewedJan 1, 2020

Targeting androgen regulation of TMPRSS2 and ACE2 as a therapeutic strategy to combat COVID-19

Qu Deng, Reyaz ur Rasool, Ronnie M. Russell…·Irfan Ahmed Asangani

This study shows androgen regulates ACE2 and TMPRSS2, both critical for SARS-CoV-2 entry, and demonstrates that inhibiting TMPRSS2 or androgen signaling reduces viral entry.

104 citations

humanmouse

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