Spatial proteomics reveals CD8+ T cell signatures and cellular niches associated with active HIV-1 replication in lymph nodes
Candace C. Liu, Marta Calvet‐Mirabent, Angie Spence…·Enrique Martín‐Gayo
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Stanford MedicineORCID 0000-0003-1486-8567Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Candace C. Liu, Marta Calvet‐Mirabent, Angie Spence…·Enrique Martín‐Gayo
Erin McCaffrey, Alea C. Delmastro, Isobel Fitzhugh…·Michael Angelo
This study identifies hypoxia as a key driver of immune dysfunction in TB granulomas, correlating with bacterial persistence.
Jolene S. Ranek, Noah F. Greenwald, Mako Goldston…·Michael Angelo
QUICHE identifies low-prevalence cellular niches in spatial datasets, outperforming existing methods, and reveals structural anti-tumor immune responses in TNBC.
Kausalia Vijayaragavan, Bryan J. Cannon, Dmitry Tebaykin…·Sean C. Bendall
This study uses spatial proteomics to analyze human brain tissues and identifies proteopathies and cell interactions in Alzheimer's disease.