MicrobiologybioRxivPreprint
Typhoid toxin of Salmonella enterica induces ISG15 response mediating host cell survival and bacterial dissemination
Daniel S Stark, Michelle King, Angela EM Ibler…·Daniel Humphreys
This study identifies ISG15 as a key host defense mechanism against Salmonella typhoid toxin, showing it promotes cell survival and reduces bacterial burden through a STING-dependent pathway.
DOI 10.1101/2025.04.29.649991