Author

Carissa Lee

Stanford Cardiovascular InstituteORCID 0000-0003-1523-9770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Sean M. WuiD· 2 shared Soah LeeiD· 2 shared A PaascheiD· 1 shared Adrija K. Darsha· 1 shared Aimee BeckiD· 1 shared Alessandra MorettiiD· 1 shared Alicia LundbyiD· 1 shared Alison Schroer Vander RoestiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Sean M. WuORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 6, 2026

Beta-Adrenergic Stimulation and MYH7 G256E Mutant Gene Dosage Drive Hypertrophic Cardiomyopathy Phenotype Penetrance

Paul V. Heinrich, Raina M. Jung, Jonathan Samuel Achter…·Sean M. Wu

This study investigates factors influencing HCM phenotype penetrance by comparing MYH7 mutations in isogenic hiPSC-CMs and shows that beta-adrenergic stimulation and gene dosage affect disease expression.

DOI 10.64898/2026.06.02.729411

humanbulk RNA-seq

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Developmental BiologyeLifePeer-reviewedJun 5, 2023

Combined Lineage Tracing and scRNA-seq Reveals Unexpected First Heart Field Predominance of Human iPSC Differentiation

Francisco X. Galdos, Carissa Lee, Soah Lee…·Sean M. Wu

The paper uses lineage tracing and scRNA-seq to show that human iPSC differentiation predominantly generates left ventricular cardiomyocytes from the first heart field.

49 citationstop 3%

humanscRNA-seq

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