Author

A Paasche

Heidelberg UniversityORCID 0000-0001-6882-1428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:mouse· 1

Frequent Co-Authors

Constanze SchmidtiD· 2 shared Felix WiedmanniD· 2 shared Alessandra MorettiiD· 1 shared Alicia LundbyiD· 1 shared Alison Schroer Vander RoestiD· 1 shared Ana KojiciD· 1 shared Brock RobertsiD· 1 shared Carissa LeeiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Constanze SchmidtORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologyJournal of Molecular and Cellular CardiologyPeer-reviewedJul 30, 2026

Transcriptional regulation of the TASK-1 potassium channel by ETV1 -Implications for atrial excitability

Moritz Beck, Felix Wiedmann, Kraft Manuel…·Constanze Schmidt

This study shows ETV1 directly regulates TASK-1 expression and contributes to atrial electrical remodelling, suggesting ETV1 as a potential therapeutic target for atrial fibrillation.

DOI 10.1016/j.yjmcc.2026.07.009

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJun 6, 2026

Beta-Adrenergic Stimulation and MYH7 G256E Mutant Gene Dosage Drive Hypertrophic Cardiomyopathy Phenotype Penetrance

Paul V. Heinrich, Raina M. Jung, Jonathan Samuel Achter…·Sean M. Wu

This study investigates factors influencing HCM phenotype penetrance by comparing MYH7 mutations in isogenic hiPSC-CMs and shows that beta-adrenergic stimulation and gene dosage affect disease expression.

DOI 10.64898/2026.06.02.729411

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 17, 2026

Disruption of RBM20 causes atrial electrophysiological disturbances

L Weirauch, Felix Wiedmann, Laura Schraft…·Constanze Schmidt

This study examines the effects of RBM20-R636Q mutation on atrial electrophysiology and evaluates SGLT inhibitors as potential therapeutics for atrial remodeling and arrhythmias.

DOI 10.64898/2026.03.14.711772

mouseelectronic health records

𝕏 PostBluesky