Developmental BiologyNature GeneticsPeer-reviewed
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation
Chiara Anania, Rafael D. Acemel, Johanna Jedamzick…·Darío G. Lupiáñez
The paper investigates how clustered-CTCF boundaries function in vivo, showing that individual CTCF sites can override other factors and that insulation strength modulates gene expression and phenotypes.