Author

Sonal Dalvi

University of Rochester MedicineORCID 0000-0003-1561-4622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

Anthony L. CookiD· 2 shared Jimin HaniD· 2 shared Ruchira SinghiD· 2 shared Alex William HewittiD· 1 shared Alison M. HefferiD· 1 shared Amit ChatterjeeiD· 1 shared Chad A. GallowayiD· 1 shared Cheyenne Reuben-ThomasiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Anthony L. CookORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 10, 2025

A 3D iPSC retina model reveals non-cell-autonomous and non-neuronal mechanism of photoreceptor degeneration in a lysosomal storage disorder.

Jimin Han, Nathaniel Foley, Sonal Dalvi…·Ruchira Singh

This study uses a 3D iPSC retina model to show that acid ceramidase deficiency causes sphingolipid metabolism changes and photoreceptor degeneration in CLN3 disease, with therapeutic potential for rhAC.

DOI 10.1101/2025.07.10.664233

humanmultiple species

𝕏 PostBluesky

Cell BiologyInvestigative Ophthalmology & Visual SciencePeer-reviewedNov 13, 2024

Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease.

Jimin Han, Sueanne Chear, Jana Talbot…·Ruchira Singh

This study investigates how CLN3 mutations impair phagocytosis and cause photoreceptor degeneration in CLN3 disease using patient-derived cells and a miniswine model.

6 citations

mouseproteomics

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