Developmental BiologyStem Cell ReportsPeer-reviewed
Human iPSC-Based Model Reveals NOX4 as Therapeutic Target in Duchenne Cardiomyopathy
Robin Duelen, Domiziana Costamagna, Guillaume Gilbert…·Maurilio Sampaolesi
This study uses DMD patient iPSCs to model cardiomyopathy, identifies NOX4 as a therapeutic target due to its role in ROS production, and shows interventions that reduce oxidative stress and improve cell survival.
29 citations