NeurosciencebioRxivPreprint
Isotope Encoded Chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity
Jack I. Wood, Maciej Dulewicz, Junyue Ge…·Jörg Hanrieder
This paper uses isotope-encoded mass spectrometry imaging and single plaque transcriptomics to track Aβ plaque maturation and its impact on synaptic function and toxicity in Alzheimer's disease.