Mara Martín-Alonso

The paper identifies Prostaglandin E2 as a key mediator of crosstalk between intestinal smooth muscle tissue and epithelium in tumor development, showing reciprocal effects on both cell types.

This study shows that intestinal-epithelial LSD1 deletion leads to increased pathogenesis in inflammatory and infectious disease models by impairing cytoskeletal organization and goblet cell effector responses.

This study identifies LSD1 as a repressor of a neonatal/reparative gene program in adult intestinal epithelium, showing its role in Paneth cell differentiation and regenerative capacity.