Author

Giancarlo Troncone

Federico II University HospitalORCID 0000-0003-1630-5805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Francesco PepeiD· 2 shared Aitor Rodríguez‐CasanovaiD· 1 shared Alexandre HarléiD· 1 shared Alexis RapiniD· 1 shared Anes Hadjadj AouliD· 1 shared Ángel Díaz‐LagaresiD· 1 shared Angela CelettiiD· 1 shared Anna Maria CarilloiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Francesco PepeORCID

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3 papers

Recent·Most cited

Cancer BiologyAPOPTOSISPeer-reviewedJul 14, 2026

KRAS-Mediated CCDC6 Degradation Drives xCT Upregulation and Ferroptosis Evasion

Daniela Criscuolo, Rosaria Catalano, Carmela Baviello…·Angela Celetti

This study identifies a KRAS/CCDC6/xCT signaling axis that promotes ferroptosis resistance in KRAS-mutated cancers by inhibiting CCDC6 degradation, which enhances ATF4 activity and xCT expression.

DOI 10.1007/s10495-026-02400-4

humanproteomics

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Cancer BiologyThyroidPeer-reviewedDec 2, 2025

Type 2 Deiodinase in Cancer-Associated Fibroblasts is required to sustain growth of poorly and undifferentiated thyroid cancer

Maria Angela De Stefano, Cristina Luongo, Tommaso Porcelli…·Domenico Salvatore

This study identifies type 2 deiodinase (D2) in cancer-associated fibroblasts as essential for sustaining growth of poorly differentiated and anaplastic thyroid cancers through local thyroid hormone metabolism.

DOI 10.1177/10507256251401458

mousehuman

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Genetic & Genomic MedicineJournal of Molecular DiagnosticsPeer-reviewedSep 25, 2025

Analytical Validation of a Pan-Cancer NGS Assay for In-House Liquid Biopsy Testing: An International Multicenter Study

Gaëlle Lescuyer, Alexandre Harlé, Hari Shankar Kumar…·Lea Francoise Payen

This study validates a pan-cancer NGS assay for liquid biopsy testing across multiple centers, showing high sensitivity and specificity for detecting genomic alterations in cfDNA.

3 citations

humanwhole-exome sequencing

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