Author

Jaclyn Swan

La Trobe UniversityORCID 0000-0003-1633-9239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ajit P VarkiiD· 1 shared Anoopjit Singh KooneriD· 1 shared Brian J. LiniD· 1 shared Cesia Gonzalez· 1 shared Chih‐Ming TsaiiD· 1 shared Ching-Wen Tseng· 1 shared Christopher B. ToomeyiD· 1 shared Elisabet BjånesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Ajit P VarkiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence

Xin Du, Ching-Wen Tseng, Elisabet Bjånes, Hunter Gage, Jaclyn Swan, Chih‐Ming Tsai, Irshad A. Hajam, Cesia Gonzalez, Brian J. Lin, Victor Nizet, George Y. Liu

This study shows that vaccine efficacy against Staphylococcus aureus alpha toxin decreases in aged mice due to reduced ADAM10 activity and myeloid cell dysfunction.

JCI Insight · Jun 8, 2026Peer-reviewedMicrobiology

The sialome of the retina, alteration in age-related macular degeneration (AMD) pathology and potential impacts on Complement Factor H

Jaclyn Swan, Christopher B. Toomey, Max Bergstrand, Héctor Cuello, Jesse Robie, Hai Yu, Yue Hua Yuan, Anoopjit Singh Kooner, Xi Chen, Jutamas Shaughnessy, Sanjay Ram, Ajit P Varki, Pascal Gagneux

This study characterizes the sialome of the human retina and identifies alterations in age-related macular degeneration (AMD) that may impact complement factor H binding.

Investigative Ophthalmology & Visual Science · Jun 27, 2025Peer-reviewedBiochemistry