BiochemistryCell Death and DifferentiationPeer-reviewed
The kinase domain of RIPK3 tunes its scaffolding functions
Shene Chiou, Christopher R. Horne, Komal M. Patel…·James M. Murphy
This study compares three RIPK3 kinase-dead variants to show that their scaffolding functions differ based on kinase domain conformation, not just kinase activity, and highlights implications for inhibitor development.
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