Marino Arroyo

The paper shows that keratin bundling in epithelial cells under stretch allows the nucleus to escape its keratin cage, providing a mechanism for tissue adaptation to mechanical stress.

This paper introduces a strategy to program tissue shape transformations through nematic organization of cellular forces, demonstrating reproducible 3D shape generation upon tissue detachment.

The paper develops a unified framework connecting sub-cellular actomyosin dynamics to tissue mechanics, explaining various epithelial behaviors under stretch.

The paper develops a continuum theory for curved epithelial shells by coarse-graining a 3D vertex model of active gel cellular surfaces, showing its accuracy in capturing buckling dynamics and the necessity of Cosserat theory for apicobasal tension asymmetry.

This study investigates the mechanics of epithelial buckling by combining experiments and simulations, revealing multiscale wrinkling dynamics and how they can be controlled through curvature and contractility.

This paper introduces 3D-TFM to measure cell-substrate forces in 3D environments and shows cells switch from contractile to extensile behavior as volume decreases.