Pau Guillamat

Guidance of cellular nematics into shape-programmable living surfaces

This paper introduces a strategy to program tissue shape transformations through nematic organization of cellular forces, demonstrating reproducible 3D shape generation upon tissue detachment.

Cardiac fibroblast cellular anisotropy is determined by YAP-dependent cellular contractility and ECM production

This study shows YAP in cardiac fibroblasts controls ECM structure and fibroblast alignment, affecting cardiomyocyte function and tissue integrity.

Actin dynamics sustains spatial gradients of membrane tension in adherent cells

The paper demonstrates that adherent cells maintain spatial gradients of membrane tension through actin dynamics and membrane-cortex attachments, with tension lowest at adhesion edges and highest at protrusions.