Sławomir Gołda

Risperidone regulates the expression of schizophrenia-related genes in the murine forebrain

This study shows risperidone alters gene expression in specific brain regions of mice, with 21 of the affected genes linked to schizophrenia.

L-DOPA induces spatially discrete changes in gene expression in the forebrain of mice with a progressive loss of dopaminergic neurons

The paper examines L-DOPA-induced gene expression changes in the forebrain of mice with progressive dopaminergic neuron loss, identifying region-specific effects and novel genes involved in nonmotor PD symptoms.

μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cord

The paper identifies a long 3' untranslated region in the primary Oprm1 transcript in mice, with additional variants expressed at lower levels.

Oligogenic risk model for Gilles de la Tourette syndrome reveals a genetic continuum of tic disorders

The paper constructs an oligogenic risk model for tic disorders using whole-genome sequencing data, revealing a genetic continuum from healthy individuals to severe Gilles de la Tourette syndrome cases.

Loss of mu and delta opioid receptors on neurons expressing dopamine receptor D1 has no effect on reward sensitivity

This study shows that knocking down mu and delta opioid receptors in dopamine receptor D1-expressing neurons does not impair reward sensitivity or related behaviors.