Mario Faretta

The paper identifies a RAC1-PLCγ2 axis that decodes EGFR ligand bias by linking receptor trafficking to metabolic programs supporting cell migration.

This study classifies and maps cell types in normal human lymph nodes using high-dimensional spatial proteomics, revealing novel cell subsets and interactions.

This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.

The paper identifies and characterizes novel dendritic cell subsets in tonsils using high-parameter imaging and bioinformatics, revealing spatial interactions with T and B cells.