Author

Simone Pelicci

European Institute of OncologyORCID 0000-0003-3539-8613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Mario FarettaiD· 2 shared Pier Paolo Di FioreiD· 2 shared Sara SigismundiD· 2 shared Stefano FreddiiD· 2 shared Alessandro CuomoiD· 1 shared Andrea BasileiD· 1 shared Andrea Francesco BenvenutoiD· 1 shared Andrea RaimondiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Mario FarettaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 4, 2026

Decoding EGFR ligand bias through an endocytic organelle platform

Gorana Jendrisek, D. Mesa, Stefano Freddi…·Sara Sigismund

The paper identifies a RAC1-PLCγ2 axis that decodes EGFR ligand bias by linking receptor trafficking to metabolic programs supporting cell migration.

1 citation

humanproteomics

𝕏 PostBluesky

Cancer BiologyAdvanced SciencePeer-reviewedJan 30, 2026

Endocytic control of cell-autonomous and non-cell-autonomous functions of p53

Roberta Cacciatore, Andrea Basile, Stefano Freddi…·Pier Paolo Di Fiore

This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.

DOI 10.1002/advs.202513765

humanproteomics

𝕏 PostBluesky