Author

Dennis R. Thomas

Cold Spring Harbor LaboratoryORCID 0000-0003-1691-2023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aashish SrivastavaiD· 1 shared Abhishek MazumderiD· 1 shared Achillefs N. KapanidisiD· 1 shared Andrew P. MayiD· 1 shared Changsheng ZhangiD· 1 shared Christopher M. AdamsiD· 1 shared David DegeniD· 1 shared Diego Duchi· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Aashish SrivastavaORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedMay 21, 2020

Methods Matter -- Standard Production Platforms For Recombinant AAV Produce Chemically And Functionally Distinct Vectors

Neil G. Rumachik, Stacy Alyse Malaker, Nicole Poweleit…·Nicole K. Paulk

This study compares rAAV production methods using different host cells, finding chemically and functionally distinct vectors with differences in PTMs, methylation, and potency.

156 citationstop 1%

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Molecular BiologyMolecular CellPeer-reviewedMar 29, 2018

Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3)

Wei Lin, Kalyan Das, David Degen…·Achillefs N. Kapanidis

This paper reports the cryo-EM structure of Mycobacterium tuberculosis RNAP holoenzyme bound to fidaxomicin, revealing its unique binding site and mechanism of transcription inhibition.

106 citationstop 2%

experimental assay

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