Zhihai Qiu

The paper introduces @fUS, an agentic transcranial fUS imaging platform that enables functional brain imaging in mice with high spatial and temporal resolution, supporting longitudinal studies without surgery.

This study characterizes the spatiotemporal response properties of fUS-CBV signals in mice during whisker stimulation, showing they retain structured information for reliable decoding.

The paper shows that ventricular expansion in mice links hyperosmotic stress to thirst by mechanically activating candidate mechanosensitive channels.

This study simulates low-intensity transcranial ultrasound stimulation (TUS) to identify optimal pathways for targeting the hippocampus in humans.

This paper introduces a miniaturized functional ultrasound imaging system for freely moving mice, achieving high-resolution brain activity mapping with improved accessibility and performance.

This study shows ultrasound directly activates sparse neurons in deafened mice, modulates visual circuits, and confirms direct mechanical effects independent of auditory input.

This study uses functional ultrasound to monitor brain activity in developing mice and non-human primates, revealing neural activity patterns and responses to external stimuli.

This study shows that Piezo1 mediates ultrasound neuromodulation in the brain by demonstrating reduced neuronal responses in Piezo1 knockout mice.

This study demonstrates that sonogenetics can selectively activate defined neural circuits and induce specific behaviors in freely moving mice through ultrasound stimulation.

This paper demonstrates a method using gas-filled nanostructures to enhance and selectively control ultrasound neuromodulation of neurons.