Author

Gregory E. Dyson

Wayne State UniversityORCID 0000-0001-9783-8464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Ahmet B. ÇağlayaniD· 2 shared Allan M. JohanseniD· 2 shared Amro AboukameeliD· 2 shared Asfar Sohail AzmiiD· 2 shared Bassel F. El‐RayesiD· 2 shared Boris PascheiD· 2 shared Eliza Wright BealiD· 2 shared Fulya Koksalar AlkaniD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Ahmet B. ÇağlayanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genomic and Transcriptomic Landscapes of MEN1-Wild-Type Low-Grade Metastatic Pancreatic NETs Uncover Key Oncogenic Drivers and Targetable Pathways

Md. Hafiz Uddin, Zaid K Mahdi, Irfana Muqbil, Brendon Herring, Rose J. Bart, Husain Yar Khan, Yiwei Li, Amro Aboukameel, Sahar F. Bannoura, Hugo Jimenez, Allan M. Johansen, Mohammad Najeeb Al-Hallak, Ibrahim Hanna Azar, Amr Mohamed, Tarik H. Hadid, , Asfar S. Azmi

This study identifies key oncogenic pathways and targetable genes in MEN1-wild-type low-grade pancreatic NETs that drive metastasis, offering a therapeutic strategy based on pathway intensity rather than mutation count.

International Journal of Biological Sciences · Sep 3, 2026Peer-reviewedCancer Biology

S100A9-Dependent CXCR2hi Neutrophils Mediate Systemic Immune Suppression and Checkpoint Resistance in Metastatic TNBC

Fulya Koksalar Alkan, Ahmet B. Çağlayan, Hilmi Kaan Alkan, Eunmi Lee, Raziye Piranlioglu, Cordarryl Jones, Max Alimadadi, Elayne M. Benson, Alicia H. Arnold, Adriana Langer Gramer, Thomas Vogl, Gregory E. Dyson, Ahmed Chadli, Mustafa Güzel, Sabine Kasimir‐Bauer, , Hasan Körkaya

This paper identifies a TGF-β/S100A9/CXCR2 axis in metastatic TNBC that drives neutrophil expansion and immune suppression, with S100A9 loss enhancing immunotherapy response.

bioRxiv · Jul 8, 2026 · PreprintCancer Biology

Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma

Husain Yar Khan, Mohammed Najeeb Al Hallak, Amro Aboukameel, Sahar F. Bannoura, Md. Hafiz Uddin, Adeeb A. Aboukameel, Fulya Koksalar Alkan, Ahmet B. Çağlayan, Hilmi Kaan Alkan, Bin Bao, Hugo Jimenez, Allan M. Johansen, Callum T. McGrath, Grayson Barker, Khalil Choucair, , Asfar Sohail Azmi

This paper shows that combining Eltanexor and MRTX1133 improves efficacy in KRASG12D mutant PDAC by overcoming resistance and reducing tumor growth.

bioRxiv · Nov 21, 2025 · PreprintCancer Biology

The relationships between genetic ancestry, somatic mutation frequency, and histologic subtypes in high-grade endometrial cancer

Ryan Bremseth-Vining, Víctor Borda, Douglas Craig, Julie J. Ruterbusch, Julie L. Boerner, Juliana Fucinari, Rouba Ali‐Fehmi, Mohamed A. Elshaikh, Hassan Abdallah, George Larry Maxwell, Kathleen M. Darcy, Gregory E. Dyson, Thomas P. Conrads, Nicholas W. Bateman, Michele L. Coté, Timothy D. O’Connor

This study examines the relationship between genetic ancestry, somatic mutation frequency, and histologic subtypes in high-grade endometrial cancer, finding associations between local ancestry and tumor mutation burden and histologic subtypes.

bioRxiv · Jul 26, 2023 · PreprintGenomics