Author

Yufen Han

Uniformed Services University of the Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Yang DuiD· 2 shared Abhinav DeoliD· 1 shared Amro AboukameeliD· 1 shared Asfar Sohail AzmiiD· 1 shared Bjorg GudmundsdottiriD· 1 shared Francis BurrowsiD· 1 shared Jaroslaw Pawel MaciejewskiiD· 1 shared Jay YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Yang DuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Combined Menin and XPO1 inhibition drive synergistic antileukemic activity in KMT2Ar and NPM1-m AML

Md. Hafiz Uddin, Sandhya Dhiman, Yufen Han, Amro Aboukameel, Vikram Dhillon, Jeff Justin Aguilar, Steven A. Buck, Abhinav Deol, Julie L. Boerner, Lisa Polin, Linda V. Kessler, Francis Burrows, Jay Yang, Asfar Sohail Azmi, Jaroslaw Pawel Maciejewski, , Suresh Kumar Balasubramanian

This study shows that combining Menin and XPO1 inhibitors synergistically inhibits KMT2A-r and NPM1-m AML cell growth and improves survival in xenograft models.

bioRxiv · Mar 13, 2026 · PreprintCancer Biology

MLL1 complex is a critical regulator of fetal hemoglobin repression

Yufen Han, Bjorg Gudmundsdottir, Kristbjorn O. Gudmundsson, Kartik R. Roy, John F. Tisdale, Yang Du

This study identifies the MLL1 complex as a regulator of fetal hemoglobin repression and shows that targeting MEN1 or KMT2A increases fetal hemoglobin expression in erythroid cells.

bioRxiv · Mar 24, 2025 · PreprintDevelopmental Biology