Víctor Borda

The paper identifies ancestry-specific genetic loci associated with autism spectrum disorder using admixture mapping across diverse populations.

This paper introduces a coalescent-based framework to unify population structure and relatedness analysis, showing that full GRMs can replace PCs for modeling genetic covariance.

The Peruvian Genome Project collects and analyzes genomic data from native and mestizo populations in Peru to address underrepresentation in global genome databases and uncover genetic adaptations to local environments.

The paper analyzes genome-wide data from 432 Peruvian urban individuals to reveal fine-scale population structure, admixture dynamics, and demographic patterns shaped by ancient and recent events.

The paper analyzes genetic diversity in the All of Us Research Program, showing that self-identified race and ethnicity groups exhibit continuous genetic variation rather than discrete clusters, with implications for genetic association studies.

The paper introduces ClOneHORT, a method to generate synthetic genomes with high fidelity using deep generative models, achieving accurate results in downstream analyses.

This study examines the relationship between genetic ancestry, somatic mutation frequency, and histologic subtypes in high-grade endometrial cancer, finding associations between local ancestry and tumor mutation burden and histologic subtypes.

The paper conducts an X-chromosome association study in Latin American cohorts, identifying new loci linked to Parkinson Disease and replicating previous findings.

The paper examines how global and local ancestry influence the association between APOE ε4 and Alzheimer's neuropathology and cognitive outcomes in an admixed Brazilian cohort.

This study presents a high-coverage whole-genome sequencing dataset of 1,171 admixed elderly Brazilians, identifying novel variants and demonstrating the utility of WGS for genomic and clinical research in underrepresented populations.

The paper identifies a West African-associated regulatory variant with a strong female-specific effect on BMI and fat mass in Brazilian admixed populations.

The paper analyzes African genetic contributions to the Americas, showing regional ancestry patterns and admixture dynamics linked to historical factors.

This study sequenced and analyzed genomes from Native American and mestizo populations in Peru to reconstruct their demographic history and genetic admixture patterns.