Author

Bin Shen

Nanjing Maternity and Child Health Care HospitalORCID 0000-0002-8946-8448Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bin Shen1 paper · Soochow University

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Chengqi YiiD· 1 shared Chonghao CheniD· 1 shared Chu‐Xia DengiD· 1 shared Chuan CheniD· 1 shared Haiyan ZhangiD· 1 shared Hong WangiD· 1 shared Huai‐Qiang JuiD· 1 shared Jiajie HouiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Chengqi YiORCID

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2 papers

Recent·Most cited

YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity

Haiyan Zhang, Xiao-Jing Luo, Wei Yang, Zhiying Wu, Zhicong Zhao, Xin Pei, Xue Zhang, Chonghao Chen, Josh Haipeng Lei, Qingxia Shi, Qi Zhao, Yanxing Chen, Wenwei Wu, Zhao-Lei Zeng, Huai‐Qiang Ju, , Jiajie Hou

This paper shows YTHDF2 upregulation and nuclear relocation enhance CD8 T cell polyfunctionality and tumor immunity by regulating gene transcription and mitochondrial fitness.

Nature Communications · Nov 5, 2024Peer-reviewedImmunology

The dual role of N6-methyladenosine on mouse maternal RNAs and 2-cell specific RNAs revealed by ULI-MeRIP sequencing

You Wu, Xiaocui Xu, Meijie Qi, Chuan Chen, Mengying Li, Rushuang Yan, Xiaochen Kou, Yanhong Zhao, Wenqiang Liu, Yanhe Li, Xuelian Liu, Meiling Zhang, Chengqi Yi, Hong Wang, Bin Shen, , Shaorong Gao

The study reveals that m6A RNA methylation stabilizes maternal RNAs in mouse oocytes and promotes the degradation of 2-cell specific RNAs during early embryonic development.

bioRxiv · Dec 13, 2021 · PreprintDevelopmental Biology