Author

Helen Rappe Baggett

Oregon Health & Science UniversityORCID 0000-0003-1748-7356Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alysson Renato MuotriiD· 1 shared Chiara BerteottiiD· 1 shared Elisabetta CianiiD· 1 shared Giorgio MediciiD· 1 shared Giovanna ZoccoliiD· 1 shared Giulia SagonaiD· 1 shared Giuseppe GalvaniiD· 1 shared Hiroyuki NakaiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alysson Renato MuotriORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJul 26, 2021

EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.

Giorgio Medici, Marianna Tassinari, Giuseppe Galvani…·Elisabetta Ciani

This study shows that using a secretable TATk-CDKL5 protein in AAV gene therapy improves CDKL5 replacement and functional outcomes in Cdkl5 KO mice compared to native CDKL5 expression.

DOI 10.1101/2021.07.26.453746

mouseprotein sequence

𝕏 PostBluesky