Author

Giovanna Zoccoli

University of BolognaORCID 0000-0002-9670-9959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Chiara BerteottiiD· 3 shared Alessandro SilvaniiD· 2 shared Alexander Neergaard Zahid· 1 shared Alfonso UrbanucciiD· 1 shared Alysson Renato MuotriiD· 1 shared Anastasia Tsopanidou· 1 shared Antoine AdamantidisiD· 1 shared Birgitte Rahbek KornumiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Chiara BerteottiORCID

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4 papers

Recent·Most cited

Lack of Consensus for Manual Mouse Sleep Scoring Limits Implementation of Automatic Deep Learning Models

Laura Rose, Alexander Neergaard Zahid, Javier García Ciudad, Christine Egebjerg, Louise Piilgaard, Frederikke Lynge Sørensen, Mie Maar Andersen, Tessa Radovanovic, Anastasia Tsopanidou, Maiken Nedergaard, Sébastien Arthaud, Renato Marciano Maciel, Christelle Peyron, Chiara Berteotti, Viviana Lo Martire, , Birgitte Rahbek Kornum

This study shows that automatic deep learning models for mouse sleep scoring struggle to generalize across labs due to signal variability and label noise, and proposes four robust models trained on diverse data.

bioRxiv · Mar 30, 2026 · PreprintNeuroscience

Increased hippocampal epigenetic age in the Ts65Dn Mouse Model of Down Syndrome

Francesco Ravaioli, Fiorenza Stagni, Sandra Guidi, Chiara Pirazzini, Paolo Garagnani, Alessandro Silvani, Giovanna Zoccoli, Renata Bartesaghi, Maria Giulia Bacalini

The paper measures epigenetic age in Ts65Dn mice using a mouse-specific clock and finds increased hippocampal epigenetic age compared to controls, with DNA methylation changes similar to those in humans with Down syndrome.

Frontiers in Aging Neuroscience · May 21, 2024Peer-reviewedMolecular Biology

EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.

Giorgio Medici, Marianna Tassinari, Giuseppe Galvani, Stefano Bastianini, Laura Gennaccaro, Manuela Loi, Nicola Mottolese, Sara Alvente, Chiara Berteotti, Giulia Sagona, Leonardo Lupori, Helen Rappe Baggett, Giovanna Zoccoli, Maurizio Giustetto, Alysson Renato Muotri, , Elisabetta Ciani

This study shows that using a secretable TATk-CDKL5 protein in AAV gene therapy improves CDKL5 replacement and functional outcomes in Cdkl5 KO mice compared to native CDKL5 expression.

bioRxiv · Jul 26, 2021 · PreprintNeuroscience

Paternally expressed imprinted Snord116 and Peg3 regulate hypothalamic orexin neurons

Marta Pace, Matteo Falappa, Freschi Andrea, Edoardo Balzani, Chiara Berteotti, Lo Martire Viviana, Fatemeh Kaveh, Eivind J. Hovig, Giovanna Zoccoli, Matteo Cerri, Roberto Amici, Alfonso Urbanucci, Valter Tucci

This study investigates the role of the paternally expressed Snord116 gene in hypothalamic orexin neurons and its impact on sleep and metabolic functions in mice with paternal deletion of Snord116.

bioRxiv · Oct 28, 2019 · PreprintNeuroscience