Author

Lucas M. Plott

University of North Carolina at Chapel HillORCID 0000-0003-1771-642XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

David B. HilliD· 2 shared Matthew R. MarkovetziD· 2 shared Cristian RocaiD· 1 shared Deborah A. PowersiD· 1 shared Hao WangiD· 1 shared Jason A. PapiniD· 1 shared Jerome CarpenteriD· 1 shared Jonathan Cummings SchisleriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

David B. HillORCID

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2 papers

Recent·Most cited

MicrobiologymSpherePeer-reviewedJun 5, 2024

Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

Kathleen L. Furtado, Lucas M. Plott, Matthew R. Markovetz…·Rita Tamayo

This study investigates how C. difficile uses host-derived mucus for growth, metabolism, and biofilm formation, revealing metabolic shifts and potential pathogenic mechanisms.

18 citationstop 3%

humanbulk RNA-seq

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MicrobiologymBioPeer-reviewedApr 23, 2024

Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection

Matthew A. Greenwald, Suzanne L. Meinig, Lucas M. Plott…·Matthew C. Wolfgang

This study shows that increased mucin and eDNA concentrations in mucus enhance Pseudomonas aeruginosa antibiotic tolerance, and establishes an in vitro model to replicate this tolerance observed in sputum.

9 citations

humanexperimental assay

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