Author
Blake A. Madruga
University of California, Los AngelesORCID 0000-0003-1787-8314Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 28 mutual co-author links5 papers
Recent·Most cited
- BioengineeringbioRxivPreprint
Transverse Sheet Illumination Microscopy (TranSIM): A High-Speed Platform for Large-Scale Volumetric Imaging
Javier Carmona, Blake A. Madruga, Steve Mendoza…·K. Arisaka
TranSIM is a high-speed volumetric imaging system that captures large-scale neural activity with reduced bandwidth constraints and improved spatial resolution.
DOI 10.1101/2025.03.14.642160 - NeurosciencebioRxivPreprint
Open-source, high performance miniature multiphoton microscopy systems for freely behaving animals
Blake A. Madruga, Conor C. Dorian, Megha Sehgal…·Peyman Golshani
The paper describes an open-source miniature 2-photon microscope for recording calcium dynamics in freely behaving mice during various experimental conditions.
- NeuroscienceNature MethodsPeer-reviewed
A positively tuned voltage indicator reveals electrical correlates of calcium activity in the brain
Stephen W. Evans, Dongqing Shi, Mariya Chavarha…·Michael Z. Lin
This paper introduces positively tuned GEVIs that enhance spike detection in vivo with standard imaging systems, offering higher temporal resolution than calcium indicators.
99 citationstop 1% - NeurosciencebioRxivPreprint
Voltage imaging reveals that hippocampal interneurons tune memory-encoding pyramidal sequences
Jiannis Taxidis, Blake A. Madruga, Maxwell D Melin…·Peyman Golshani
The paper uses voltage imaging to show that hippocampal interneurons modulate memory-encoding pyramidal sequences through inhibition, enhancing signal-to-noise ratios during odor-cued working memory tasks.