BLTP2 orchestrates lysobisphosphatidic acid synthesis and exosome biogenesis via SCAMP3-dependent ER contacts in tumorigenesis
Jingru Wang, Dongchen Li, Yazhou Liu, Tiantian Zhou, Juan Xiong, Wei-Ke Ji
This study identifies BLTP2's role in lysobisphosphatidic acid synthesis and exosome biogenesis through SCAMP3-dependent ER-MVB contacts, showing its importance in cell proliferation and tumorigenesis.
bioRxiv · Apr 17, 2025 · PreprintCell Biology