Author

Naila Kuhlmann

Montreal Neurological Institute and HospitalORCID 0000-0003-1788-9427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:electronic health records· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anouar KhayachiiD· 3 shared Anusha KameshiD· 3 shared Austen J. MilnerwoodiD· 3 shared Agostinho SantosiD· 1 shared Alessia PietrantonioiD· 1 shared Andrea PietrantonioiD· 1 shared Ariel R. Ase· 1 shared Boris ChaumetteiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Anouar KhayachiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 16, 2026

Sex- and age-dependent control of dopamine function by LRRK2, and rapid reversal of dopamine release deficits in the LRRK2-G2019S knock-in mouse model of Parkinson's Disease.

Christina Gentle, Anusha Kamesh, Jeanne F. Madranges…·Austen J. Milnerwood

The paper investigates how LRRK2 activity affects dopamine release in mice, showing age- and sex-dependent changes and rapid reversal with inhibition in certain groups.

DOI 10.64898/2026.10.14.759167

mouseexperimental assay

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Neurosciencenpj Parkinson s DiseasePeer-reviewedMay 3, 2025

Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition

Anusha Kamesh, Chelsie Kadgien, Naila Kuhlmann…·Austen J. Milnerwood

This study shows that VPS35(D620N) mutation leads to increased glutamate and dopamine transmission in mice, which can be reversed by LRRK2 inhibition.

1 citation

mouseelectronic health records

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NeuroscienceJournal of Psychiatry and NeurosciencePeer-reviewedMay 1, 2021

Chronic lithium treatment alters the excitatory/inhibitory balance of synaptic networks and reduces mGluR5-PKC signaling

Anouar Khayachi, Ariel R. Ase, Calwing Liao…·Austen J. Milnerwood

This study shows chronic lithium treatment reduces neuronal excitability and shifts the excitatory/inhibitory balance toward inhibition in mouse cortical neurons.

30 citationstop 5%

mouseelectronic health records

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