David R. Sherwood

This study shows that newer insecticides like flupyradifurone cause dopaminergic neurodegeneration in C. elegans, marked by dendritic blebbing and oxidative stress, which can be mitigated by antioxidants or genetic interventions.

The paper identifies specialized high-capacity mitochondria in C. elegans anchor cells that generate elevated ATP to fuel basement membrane invasion.

The paper catalogs endogenously tagged proteins in C. elegans, identifies gaps in coverage, and provides a database with tools for designing knock-in experiments.

The paper develops a method to visualize ECM dynamics in zebrafish during development and regeneration, revealing distinct expression patterns and dynamic behaviors of specific ECM proteins.

This study evaluates AAV9 transduction efficiency in Alport syndrome podocytes, finding enhanced transduction in Alport podocytes both ex vivo and in vivo.

The paper shows that nuclear contact and positioning enhance basement membrane invasion efficiency in C. elegans anchor cells.

The paper shows that fibulin-1 is delivered on-demand to the basement membrane during stretching in C. elegans, maintaining its structure and enabling repeated organ expansion.

This study identifies MOZT, a mitophagy process at the oocyte-to-zygote transition, which removes damaged mitochondria and preserves mitochondrial health, ensuring species continuity.

The paper constructs a collagen IV fluorophore knock-in toolkit in C. elegans to study -chain diversity and basement membrane defects in collagen IV mutants.

The paper shows that de novo lipid synthesis and polarized prenylation are essential for cell invasion through basement membrane in C. elegans anchor cells.

The paper investigates how collagen and DDR-2 signaling coordinate integrin adhesion between adjacent tissues in C. elegans.

The paper describes a mounting protocol for live imaging of C. elegans larvae and adults using light sheet fluorescence microscopy.

The paper identifies hemicentin and fibulin-1 as initiators of basement membrane-BM linkage and shows type IV collagen strengthens this linkage during mechanical stress in C. elegans.