Qiuyi Chi

The paper identifies specialized high-capacity mitochondria in C. elegans anchor cells that generate elevated ATP to fuel basement membrane invasion.

The paper catalogs endogenously tagged proteins in C. elegans, identifies gaps in coverage, and provides a database with tools for designing knock-in experiments.

The paper shows that fibulin-1 is delivered on-demand to the basement membrane during stretching in C. elegans, maintaining its structure and enabling repeated organ expansion.

This study identifies MOZT, a mitophagy process at the oocyte-to-zygote transition, which removes damaged mitochondria and preserves mitochondrial health, ensuring species continuity.

The paper constructs a collagen IV fluorophore knock-in toolkit in C. elegans to study -chain diversity and basement membrane defects in collagen IV mutants.

The paper shows that de novo lipid synthesis and polarized prenylation are essential for cell invasion through basement membrane in C. elegans anchor cells.

The paper investigates how collagen and DDR-2 signaling coordinate integrin adhesion between adjacent tissues in C. elegans.

The paper identifies hemicentin and fibulin-1 as initiators of basement membrane-BM linkage and shows type IV collagen strengthens this linkage during mechanical stress in C. elegans.

This study shows SPARC promotes cell invasion by reducing basement membrane type IV collagen levels in C. elegans.