Michael B. Nguyen

This paper introduces a new manufacturing method for infusible extracellular matrix (iECM) using depth filtration and tangential flow filtration (DF-TFF) to improve production efficiency, concentration, and compliance with cGMP standards.

This study investigates the effects of different molecular weight components of an intravascularly infusible decellularized extracellular matrix (iECM) on vascular binding and pro-reparative gene expression after myocardial infarction.

This study uses snRNAseq to identify cell-specific pro-repair responses induced by an infusible ECM biomaterial after myocardial infarction.

This study uses spatial and single nucleus transcriptomics to analyze the regional and cell-specific effects of ECM hydrogel treatments in myocardial infarction, revealing differences in immune modulation and cardiac development between subacute and chronic administration.