Amit Sinha

Discovery of a Novel High-Salt-Adapted Archaeal AP Endonuclease using Microfluidics-Based Cell-Free Functional Metagenomics

The paper discovers a novel archaeal AP endonuclease from a salt marsh metagenome using cell-free functional metagenomics, showing its high salt tolerance and structural similarity to human APE1.

Cappable-Seq reveals the transcriptional landscape of stress responses in the bacterial endosymbiont Wolbachia

The paper uses Cappable-Seq to analyze transcriptional start sites in Wolbachia under stress conditions, revealing differential regulation and insights into gene operon organization.

High-throughput nanopore DNA sequencing of large insert fosmid clones directly from bacterial colonies

This paper introduces a method for high-throughput nanopore sequencing of fosmid clones directly from E. coli colonies, along with a bioinformatics pipeline for de novo assembly and vector trimming.

Metagenomics of culture isolates and insect tissue illuminate the evolution of Wolbachia, Rickettsia and Bartonella symbionts in Ctenocephalides spp. fleas

The paper presents genome assemblies of bacterial pathogens and endosymbionts from Ctenocephalides fleas using metagenomics and culture isolation, revealing genomic diversity and features associated with host interactions.

Multiple origins of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia

This study identifies two independent origins of filarial Wolbachia in supergroup F and shows convergent loss of bacterioferritin in filarial Wolbachia.

Genomes of the human filarial parasites Mansonella perstans and Mansonella ozzardi

The paper reports the first genomes of Mansonella perstans and Mansonella ozzardi, enabling comparative genomic analysis and insights into their biology, evolution, and drug resistance.

Complete Genome Sequence of the Wolbachia wAlbB Endosymbiont of Aedes albopictus

The paper reports the complete genome sequence of Wolbachia wAlbB from Aedes albopictus using long-read sequencing, revealing new insights into its gene content and structure.