This study identifies two independent origins of filarial Wolbachia in supergroup F and shows convergent loss of bacterioferritin in filarial Wolbachia.

Genome Biology and Evolution · May 1, 2023Peer-reviewedGenomics

Genomes of the human filarial parasites Mansonella perstans and Mansonella ozzardi

Amit Sinha, Zhiru Li, Catherine B. Poole, Richard Morgan, Laurence M. Ettwiller, Nathália F. Lima, Marcelo U. Ferreira, Fanny Fri Fombad, Samuel Wanji, Clotilde K. S. Carlow

The paper reports the first genomes of Mansonella perstans and Mansonella ozzardi, enabling comparative genomic analysis and insights into their biology, evolution, and drug resistance.

Frontiers in Tropical Diseases · Apr 3, 2023Peer-reviewedGenomics

A molecular barcode and online tool to identify and map imported infection with Plasmodium vivax

Hidayat Trimarsanto, Roberto Amato, Richard D. Pearson, Edwin Sutanto, Rintis Noviyanti, Leily Trianty, Jutta Marfurt, Zuleima Pava, Diego F. Echeverry, Tatiana M. Lopera-Mesa, Lidia Madeline Montenegro, Alberto Tobón-Castaño, Matthew J. Grigg, Bridget E. Barber, Timothy William, , Sarah Auburn

The paper develops a molecular barcode and online tool to identify and map imported Plasmodium vivax infections using SNP analysis and machine learning.

Communications Biology · Dec 23, 2022Peer-reviewedMolecular Biology

Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: a case study in the Amazon Basin

Rodrigo M. Corder, Marcelo U. Ferreira, M. Gabriela M. Gomes

The paper models residual Plasmodium vivax malaria transmission in the Amazon Basin, finding that 20% of hosts contribute 86% of the malaria burden through high-risk individuals.

PLoS Computational Biology · Mar 13, 2020Peer-reviewedBioinformatics

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

Kara A. Moser, Elliott Franco Drábek, Ankit Dwivedi, Emily M. Stucke, Jonathan Crabtree, Antoine Dara, Zalak Shah, Matthew Adams, Tao Li, Priscila T. Rodrigues, Sergey Koren, Adam M. Phillippy, James B. Munro, Amed Ouattara, Benjamin C. Sparklin, , Joana Caldeira Fernandes da Silva

The paper compares genome structure, sequence, and immunogenic potential of Plasmodium falciparum strains used in vaccine trials and finds significant differences affecting vaccine efficacy.

Genome Medicine · Jan 8, 2020Peer-reviewedGenomics