Paul McVeigh

The paper identifies conserved RNAi effector genes in trematode-vectoring snails, suggesting potential for RNAi-based disease control despite lacking classical systemic and amplification components.

The paper examines how different diets affect the growth, survival, fecundity, transcriptome, and microbiome of Biomphalaria glabrata snails.

This study identifies polo-like kinase 1 (fhplk1) as a key regulator of growth in juvenile Fasciola hepatica by showing its role in stem cell proliferation and cell cycle control.

This paper identifies and characterizes neoblast-like stem cells in Fasciola hepatica, showing their self-renewal, differentiation, and radiation sensitivity, and identifies potential drug targets.

The paper identifies 6,436 putative long non-coding RNAs in Fasciola hepatica, showing distinct features from mRNAs and potential regulatory roles.

This study uses in silico analyses to characterize endocannabinoid signaling across nematodes, revealing conservation patterns and potential drug targets in parasitic species.

This paper expands the Fasciola hepatica miRNome by identifying 61 new miRNAs and provides the first developmental expression profiles and functional annotations of miRNAs in this parasite.

This study compares transcriptomic profiles of in vitro and in vivo maintained Fasciola hepatica juveniles to identify gene expression differences that may explain growth and development variations.

This study investigates RNAi dynamics in developing juvenile Fasciola hepatica, finding reduced RNAi efficacy in early stages and improved efficiency with repeated dsRNA exposure.

This paper identifies 146 GPCRs in Fasciola hepatica, including 18 unique rhodopsins, and provides ligand-receptor predictions, offering potential targets for new anthelmintic drugs.