Author

Mian Horvath

University of PennsylvaniaORCID 0000-0003-1878-8644Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Kelvin C. LukiD· 2 shared Angela Lo· 1 shared Anna Caputo· 1 shared Anna Stieber· 1 shared Anthony R. BrauniD· 1 shared Bin ZhangiD· 1 shared Chih Hung LoiD· 1 shared David Dale ThomasiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Kelvin C. LukORCID

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3 papers

Recent·Most cited

MicrobiologymSpherePeer-reviewedOct 30, 2025

Host-specific bacterial modulation of airway gene expression and alternative splicing

Mian Horvath, Hyeon Gu Kang, Te-Chia Wu…·Julia Oh

This study shows that bacterial species and individual donors differentially modulate airway gene expression and alternative splicing in human epithelial cells.

DOI 10.1128/msphere.00577-25

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceeNeuroPeer-reviewedJul 1, 2020

Snca-GFP knock-in mice reflect patterns of endogenous expression and pathological seeding

Anna Caputo, Yuling Liang, Tobias D. Raabe…·Kelvin C. Luk

This paper develops a mouse model expressing aSyn-GFP under native regulatory elements, showing it mirrors endogenous aSyn expression and pathology.

22 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintJan 9, 2020

Potent inhibitors of toxic alpha-synuclein oligomers identified via cellular time-resolved FRET biosensor.

Anthony R. Braun, Elly E. Liao, Mian Horvath…·Jonathan N. Sachs

The paper identifies potent small molecules that inhibit toxic alpha-synuclein oligomers and reduce cell death in SH-SY5Y cells using a FRET-based biosensor platform.

3 citations

humanproteomics

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