Arthur R. Wolin

This study identifies Eya3 in macrophages as a checkpoint for anti-tumor immunity in TNBC, showing that its depletion or inhibition enhances immune responses and reduces tumor growth.

The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.

The paper identifies eIF3d and eIF3e as mediators of hypoxia-induced translational control and shows that small molecules can inhibit this process.