Kate Matlin

This study identifies Eya3 in macrophages as a checkpoint for anti-tumor immunity in TNBC, showing that its depletion or inhibition enhances immune responses and reduces tumor growth.

The paper identifies eIF3d and eIF3e as mediators of hypoxia-induced translational control and shows that small molecules can inhibit this process.

This study identifies translational reprogramming via mTOR activation as a mechanism of omacetaxine resistance in multiple myeloma and suggests combination therapy with mTOR inhibitors.