Xiang Wang

This study identifies Eya3 in macrophages as a checkpoint for anti-tumor immunity in TNBC, showing that its depletion or inhibition enhances immune responses and reduces tumor growth.

The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.

This study identifies a tetrahydrocarbazole compound that potentiates multiple antibiotics against multidrug-resistant Klebsiella pneumoniae.

The paper identifies eIF3d and eIF3e as mediators of hypoxia-induced translational control and shows that small molecules can inhibit this process.

This study shows that combining EYA and PLK1 inhibitors is effective in treating neurological cancers by inducing cell death and targeting cancer stem cells.