Author

Pengwei Xing

Uppsala UniversityORCID 0000-0003-1907-1629Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Assay:ATAC-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Xingqi CheniD· 5 shared Linxuan ZhaoiD· 3 shared Miao ZhaoiD· 3 shared Fredrik J. SwartlingiD· 2 shared Lene UhrbomiD· 2 shared lidong wangiD· 2 shared Ling-Ling Lei· 2 shared Rui‐Hua XuiD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersCancer Biology

Xingqi ChenORCID

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5 papers

Recent·Most cited

Cancer BiologyCommunications BiologyPeer-reviewedAug 18, 2026

HER2 Prognostic Significance and Therapeutic Implications in Gastric Cardia Adenocarcinoma: Insights from Multi-Omics Profiling

lidong wang, pengwei xing, Xue-Ke Zhao…·Xingqi Chen

This study identifies HER2 as a prognostic marker in GCA and suggests anti-inflammatory and immune checkpoint inhibition as therapeutic strategies for HER2-negative patients.

DOI 10.1038/s42003-026-10792-x

humanwhole-exome sequencing

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Cancer BiologybioRxivPreprintJan 17, 2026

Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcome

Inês Neves, Xi Lü, Veera Jokinen…·Lene Uhrbom

The paper identifies a distinct peritumoral glioblastoma cell population with unique epigenetic and phenotypic features associated with poor patient outcomes.

DOI 10.64898/2026.01.16.699862

humansnRNA-seq

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GenomicsGenome ResearchPeer-reviewedJan 1, 2022

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Hua Zhang, Vamsi Krishna Polavarapu, Pengwei Xing…·Xingqi Chen

This paper introduces FFPE-ATAC, a method for profiling chromatin accessibility in formalin-fixed paraffin-embedded tissues, demonstrating its effectiveness with colorectal cancer samples.

63 citations

humanATAC-seq

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GenomicsNature CommunicationsPeer-reviewedNov 11, 2021

Extrachromosomal DNA is associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma

Xueke Zhao, Pengwei Xing, Xin Song…·Lidong Wang

The paper investigates extrachromosomal DNA (ecDNA) in gastric cardia adenocarcinoma, finding associations with chromothripsis, DNA damage, and prognosis based on oncogene amplicons.

57 citationstop 2%

humanwhole-exome sequencing

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NeurosciencebioRxivPreprintFeb 22, 2021

Conserved cell-lineage controlled epigenetic regulation in human and mouse glioblastoma stem cells determines functionally distinct subgroups

Xi Hua Lu, Naga Prathyusha Maturi, Malin Jarvius…·Xingqi Chen

The paper identifies functionally distinct subgroups of glioblastoma stem cells (GSCs) by analyzing cross-species chromatin accessibility, showing that epigenetic regulation is controlled by developmental origin.

DOI 10.1101/2021.02.22.431953

mousehuman

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