Naonobu Fujita

This study shows autophagy is essential for sarcoplasmic reticulum remodeling during Drosophila muscle metamorphosis, with SR membranes incorporated into autophagosomes.

This study identifies LUBEL/RNF31 as a key regulator of T-tubule biogenesis through linear ubiquitination, showing its interaction with Amphiphysin and role in membrane tubulation.

The paper uses time-course RNA-seq to study muscle remodeling in Drosophila, identifying BNIP3-mediated mitophagy as critical for mitochondrial degradation during this process.

This study identifies the PI(4,5)P2 pathway's role in T-tubule formation and muscle function using Drosophila models.