Quee-Lim Ch'ng

HCR3.0 RNA-FISH linked to RS-FISH spot detection labels transcripts in C. elegans embryos, larvae and adults, and yields per-neuron counts of short insulin-like peptide mRNAs in L2 larvae.

This study shows that the neuropeptide receptor NMUR-1 modulates insulin receptor signaling in C. elegans to buffer survival differences caused by bacterial strains.

This paper introduces SQUASSH, a convolutional neural network that fits structural models to fluorescence microscopy data to quantify variability across biological scales.

The paper shows that specific sensory neurons and insulin-like peptides in C. elegans influence oogenesis and fertilization based on food type.

This study shows how C. elegans maintains food-responsiveness across temperature changes through a multicellular gene network involving TGF-β and serotonin signaling.